Thousands of supporters of ousted president Mohammed Mursi are on the streets in cities across Egypt, urging a "Day of Rage" after Wednesday's crackdown in Cairo in which over 600 people were killed.
The army deployed dozens of armoured vehicles on major roads in Cairo.
Up to 50 people have been killed and many more wounded during protests in central Cairo.
Five people have been killed and 70 wounded in protest clashes in Egypt's Fayoum, according to a local hospital official.
Medical sources said four protesters died in clashes in the northeastern city of Ismailia, with eight dead reported in the Mediterranean port of Damietta.
The Interior Ministry has said police will use live ammunition against anyone threatening state installations.
Tear gas was fired and shooting was heard where pro-Mursi supporters were protesting in Cairo.
Two witnesses said they saw protesters throw petrol bombs at a police station near the square.
Violence was also reported in Egypt's second city Alexandria and in the Nile Delta city of Tanta.
Scuffles broke out in Cairo and a police conscript was killed in a drive-by shooting in the north of the capital, state news agency MENA reported.
At least 623 people died and thousands were wounded on Wednesday when police cleared out two protest camps in Cairo in protest at the overthrow of Mr Mursi.
The Muslim Brotherhood called for a nationwide march of millions to show anger at Wednesday's security crackdown.
It said it would not retreat in its showdown with army commander General Abdel Fattah al-Sisi.
"After the blows and arrests and killings that we are facing, emotions are too high to be guided by anyone," said Brotherhood spokesman Gehad El-Haddad.
A Brotherhood statement called for a nationwide "march of anger" by millions of supporters on Friday after noon prayers.
The Brotherhood accuses the military of staging a coup when it ousted Mr Mursi. Liberal and youth activists who backed the military saw the move as a positive response to public demands.
In calling for a "Friday of anger," the Brotherhood used the same name as that given to the most violent day of the 2011 uprising against former president Hosni Mubarak.
That day, 28 January 2011, marked the protesters' victory over the police, who were forced to retreat while the army was asked to step in.
In a counter move, a loose liberal and leftist coalition, the National Salvation Front, called on Egyptians to protest on Friday against what it said was "obvious terrorism actions" conducted by the Muslim Brotherhood.
Travel warnings issued over situation in Egypt
The Department of Foreign Affairs has advised Irish citizens to avoid non-essential travel to Egypt, with the exception of the Red Sea Resorts.
The Embassy in Cairo remains open and is monitoring the situation.
Irish people are also urged to comply with curfew conditions and to monitor the media for updates on the security situation.
Irish people already in Egypt should "exercise extreme caution" and "avoid all protests and demonstrations".
Germany has extended its travel alert for Egypt to include the Red Sea tourist resorts which had previously been excluded from its travel alerts, though increased caution had been recommended.
"We advise against travel to Egypt and advise urgently against travel to Cairo, upper Egypt and the Nile delta," the spokesman said.
"Foreign Minister Guido Westerwelle urges German citizens to take this travel advice very seriously."
The alert is short of a full travel warning, however, which would entail tourists being evacuated.
Meanwhile, the British Foreign Office has advised its citizens, currently on holidays in the Red Sea resort of Hurghada, to stay within the grounds of their hotels.
There were violent clashes in the area this week, although the tourist centres were not affected.
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